ALPS Medical Breakthroughs ETF (SBIO) is an ETF managed by Independent / Boutique. Its largest position is Kymera Therapeutics, Inc. (KYMR), representing 4.66% of fund assets.
ALPS Medical Breakthroughs ETF Portfolio Holdings
Source: SEC Form N-PORT institutional portfolio disclosures
- Ticker:
- SBIO
- Type:
- ETF
- Manager:
- Independent / Boutique
- Total Assets:
- —
- Report Date:
- Feb 28, 2026
- Filing Date:
- Apr 29, 2026
| Holding | Weight | Market Value | Shares |
|---|---|---|---|
|
-
Kymera Therapeutics, Inc.
|
4.66% | $6,427,842.75 | 70,365 |
|
-
Celcuity Inc.
|
3.34% | $4,607,032.11 | 41,241 |
|
-
Alkermes plc.
|
3.21% | $4,429,756.80 | 147,168 |
|
-
CG Oncology, Inc.
|
3.06% | $4,227,543.60 | 71,897 |
|
-
Mirum Pharmaceuticals, Inc.
|
3.06% | $4,227,251.16 | 45,804 |
|
-
AMICUS THERAPEUTICS INC
|
2.86% | $3,951,577.56 | 274,988 |
|
-
ACADIA PHARMACEUTICALS INC
|
2.68% | $3,703,377.84 | 150,789 |
|
-
NewAmsterdam Pharma Co N.V.
|
2.60% | $3,583,693.98 | 101,063 |
|
-
CRINETICS PHARMACEUTICALS INC
|
2.52% | $3,476,073.60 | 84,576 |
|
-
APOGEE THERAPEUTICS INC
|
2.48% | $3,421,040.00 | 48,872 |
|
-
Viking Therapeutics, Inc.
|
2.47% | $3,409,244.64 | 100,746 |
|
-
Structure Therapeutics Inc.
|
2.47% | $3,406,147.34 | 54,083 |
|
-
Xenon Pharmaceuticals Inc.
|
2.16% | $2,977,379.79 | 68,873 |
|
-
Spyre Therapeutics, Inc.
|
2.15% | $2,974,442.57 | 69,157 |
|
-
Edgewise Therapeutics, Inc.
|
2.08% | $2,872,318.40 | 94,360 |
|
-
Tarsus Pharmaceuticals, Inc.
|
2.07% | $2,857,299.20 | 37,835 |
|
-
Denali Therapeutics Inc.
|
2.01% | $2,775,278.94 | 131,033 |
|
-
IDEAYA Biosciences, Inc.
|
1.82% | $2,515,947.00 | 78,135 |
|
-
Travere Therapeutics, Inc.
|
1.72% | $2,375,573.76 | 79,744 |
|
-
APELLIS PHARMACEUTICALS INC
|
1.71% | $2,363,617.28 | 112,768 |
|
-
Vera Therapeutics, Inc.
|
1.68% | $2,324,091.83 | 56,977 |
|
-
Disc Medicine, Inc.
|
1.62% | $2,241,496.52 | 33,646 |
|
-
Dianthus Therapeutics, Inc. /DE/
|
1.53% | $2,109,030.66 | 38,214 |
|
-
Mineralys Therapeutics, Inc.
|
1.50% | $2,063,912.62 | 70,537 |
|
-
Lakefront Biotherapeutics NV
|
1.42% | $1,965,306.42 | 58,387 |
|
-
Maze Therapeutics, Inc.
|
1.42% | $1,955,309.51 | 42,889 |
|
-
Zai Lab Ltd
|
1.39% | $1,921,461.84 | 99,972 |
|
-
Stoke Therapeutics, Inc.
|
1.34% | $1,853,560.28 | 50,908 |
|
-
Nuvation Bio Inc.
|
1.31% | $1,805,853.69 | 305,559 |
|
-
Celldex Therapeutics, Inc.
|
1.29% | $1,782,110.34 | 59,226 |
|
-
Olema Pharmaceuticals, Inc.
|
1.23% | $1,696,637.80 | 70,109 |
|
-
Pharvaris N.V.
|
1.17% | $1,620,898.66 | 57,094 |
|
-
Vericel Corp
|
1.17% | $1,608,311.68 | 45,076 |
|
-
Relay Therapeutics, Inc.
|
1.15% | $1,584,964.80 | 154,480 |
|
-
Tyra Biosciences, Inc.
|
1.15% | $1,584,556.70 | 47,570 |
|
-
AGIOS PHARMACEUTICALS, INC.
|
1.14% | $1,571,143.79 | 51,973 |
|
-
Sarepta Therapeutics, Inc.
|
1.13% | $1,565,300.20 | 93,395 |
|
-
Oculis Holding AG
|
1.09% | $1,498,586.55 | 50,955 |
|
-
Amylyx Pharmaceuticals, Inc.
|
1.08% | $1,484,824.43 | 97,879 |
|
-
Oruka Therapeutics, Inc.
|
1.08% | $1,484,585.04 | 43,144 |
|
-
NOVAVAX INC
|
1.06% | $1,468,606.62 | 144,833 |
|
-
Immunocore Holdings plc
|
1.05% | $1,454,630.50 | 45,035 |
|
-
Sionna Therapeutics, Inc.
|
1.05% | $1,453,415.04 | 39,776 |
|
-
PALVELLA THERAPEUTICS, INC.
|
1.03% | $1,424,731.04 | 10,552 |
|
-
MBX Biosciences, Inc.
|
0.94% | $1,302,716.10 | 40,022 |
|
-
Zenas BioPharma, Inc.
|
0.91% | $1,260,636.70 | 47,842 |
|
-
Immatics N.V.
|
0.90% | $1,235,505.92 | 119,488 |
|
-
Rapport Therapeutics, Inc.
|
0.89% | $1,233,107.31 | 42,477 |
|
-
Corvus Pharmaceuticals, Inc.
|
0.88% | $1,215,458.64 | 66,564 |
|
-
Taysha Gene Therapies, Inc.
|
0.80% | $1,105,945.14 | 244,138 |
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