Direxion Daily S&P Biotech Bull 3X Shares (LABU) is an ETF managed by Direxion. Its largest position is APPLIED MATERIALS INC /DE (AMAT), representing 7.90% of fund assets.
Direxion Daily S&P Biotech Bull 3X Shares Portfolio Holdings
Source: SEC Form N-PORT institutional portfolio disclosures
- Ticker:
- LABU
- Type:
- ETF
- Manager:
- Direxion
- Total Assets:
- —
- Report Date:
- Apr 30, 2026
- Filing Date:
- Jun 29, 2026
| Holding | Weight | Market Value | Shares |
|---|---|---|---|
|
-
APPLIED MATERIALS INC /DE
|
7.90% | $40,990,416.22 | 40,990,416 |
|
-
APPLIED MATERIALS INC /DE
|
6.66% | $34,559,954.16 | 34,559,954 |
|
-
APPLIED MATERIALS INC /DE
|
2.78% | $14,425,305.89 | 1 |
|
-
APPLIED MATERIALS INC /DE
|
1.82% | $9,422,418.66 | 9,422,419 |
|
-
APELLIS PHARMACEUTICALS INC
|
1.53% | $7,954,537.50 | 194,250 |
|
-
APPLIED MATERIALS INC /DE
|
1.52% | $7,889,482.91 | 1 |
|
-
Revolution Medicines, Inc.
|
1.35% | $7,025,561.76 | 48,748 |
|
-
Travere Therapeutics, Inc.
|
1.33% | $6,910,502.04 | 164,067 |
|
-
ARROWHEAD PHARMACEUTICALS, INC.
|
1.18% | $6,139,841.84 | 83,558 |
|
-
Twist Bioscience Corp
|
1.17% | $6,055,595.35 | 103,603 |
|
-
Summit Therapeutics Inc.
|
1.15% | $5,984,056.62 | 278,847 |
|
-
Alkermes plc.
|
1.14% | $5,893,283.33 | 174,823 |
|
-
TG THERAPEUTICS, INC.
|
1.13% | $5,846,642.40 | 173,080 |
|
-
MADRIGAL PHARMACEUTICALS, INC.
|
1.12% | $5,820,120.11 | 11,249 |
|
-
APPLIED MATERIALS INC /DE
|
1.10% | $5,716,673.63 | 1 |
|
-
Beam Therapeutics Inc.
|
1.09% | $5,646,050.82 | 186,154 |
|
-
APOGEE THERAPEUTICS INC
|
1.04% | $5,388,347.34 | 65,006 |
|
-
Scholar Rock Holding Corp
|
1.01% | $5,240,129.25 | 112,425 |
|
-
Praxis Precision Medicines, Inc.
|
1.00% | $5,211,276.35 | 16,345 |
|
-
EXELIXIS, INC.
|
1.00% | $5,169,853.26 | 116,281 |
|
-
Mirum Pharmaceuticals, Inc.
|
0.99% | $5,149,353.27 | 52,917 |
|
-
APPLIED MATERIALS INC /DE
|
0.98% | $5,109,095.76 | 1 |
|
-
UNITED THERAPEUTICS Corp
|
0.98% | $5,093,013.90 | 8,914 |
|
-
Natera, Inc.
|
0.98% | $5,091,327.36 | 24,696 |
|
-
Celcuity Inc.
|
0.98% | $5,089,540.35 | 41,941 |
|
-
CRISPR Therapeutics AG
|
0.98% | $5,089,279.90 | 97,235 |
|
-
Krystal Biotech, Inc.
|
0.96% | $4,992,643.62 | 19,037 |
|
-
Protagonist Therapeutics, Inc
|
0.96% | $4,980,269.37 | 50,321 |
|
-
NEUROCRINE BIOSCIENCES INC
|
0.95% | $4,934,464.92 | 37,476 |
|
-
INCYTE CORP
|
0.94% | $4,886,112.49 | 51,287 |
|
-
CG Oncology, Inc.
|
0.94% | $4,883,365.80 | 73,170 |
|
-
CYTOKINETICS INC
|
0.94% | $4,880,719.09 | 76,297 |
|
-
NUVALENT INC-A
|
0.94% | $4,865,685.88 | 48,521 |
|
-
IONIS PHARMACEUTICALS INC
|
0.94% | $4,852,746.36 | 64,911 |
|
-
BridgeBio Pharma, Inc.
|
0.93% | $4,835,693.33 | 68,003 |
|
-
Vaxcyte, Inc.
|
0.93% | $4,830,369.12 | 84,388 |
|
-
Kymera Therapeutics, Inc.
|
0.93% | $4,827,961.71 | 59,553 |
|
-
BIOGEN INC.
|
0.93% | $4,823,611.52 | 25,484 |
|
-
Cogent Biosciences, Inc.
|
0.93% | $4,815,687.66 | 134,554 |
|
-
PTC THERAPEUTICS, INC.
|
0.93% | $4,809,755.68 | 73,928 |
|
-
INSMED Inc
|
0.92% | $4,748,373.90 | 34,830 |
|
-
ALNYLAM PHARMACEUTICALS, INC.
|
0.90% | $4,689,082.99 | 15,151 |
|
-
Roivant Sciences Ltd.
|
0.90% | $4,682,372.13 | 164,121 |
|
-
HALOZYME THERAPEUTICS, INC.
|
0.90% | $4,648,644.18 | 73,023 |
|
-
Arcutis Biotherapeutics, Inc.
|
0.88% | $4,574,131.02 | 196,991 |
|
-
Spyre Therapeutics, Inc.
|
0.88% | $4,561,551.50 | 61,270 |
|
-
SOLENO THERAPEUTICS INC
|
0.87% | $4,526,621.18 | 85,699 |
|
-
AbbVie Inc.
|
0.87% | $4,505,765.04 | 21,322 |
|
-
AMGEN INC
|
0.86% | $4,450,351.25 | 12,853 |
|
-
REGENERON PHARMACEUTICALS, INC.
|
0.85% | $4,431,145.02 | 6,267 |
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